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Princess Margaret Cancer Institute Toronto General Research Institute Toronto Rehabilitation Institute Toronto Western Research Institute

Princess Margaret Cancer Centre

Toronto General Research Institute

Toronto Rehab Institute

Toronto Western Research Institute

  • Located in Toronto, Ontario
  • Research foci: cancer— genomics, informatics, molecular biology, clinical trials, signalling pathways, structural biology and biophysics.
  • 361 scientists and clinician-scientists
  • $162M external funding
  • more

  • Located at the Toronto General Hospital, Toronto, Ontario
  • Research foci: cardiology, transplantation, immunology and infectious disease
  • 230 scientists and clinician-scientists
  • $73M external funding
  • more

  • Located at Toronto Rehab, Toronto, Ontario
  • Research foci: rehabilitation sciences, cardiopulmonary fitness and mobility
  • 119 scientists and clinician-scientists
  • $8M external funding
  • more

  • Located at the Toronto Western Hospital, Toronto, Ontario
  • Research foci: Neural and visual sciences, musculoskeletal disease and community and population health
  • 159 scientists and clinician-scientists
  • $35M external funding
  • more


Pancreatic Cancer: Blood Proteins Aid in Diagnosis
Nov 21, 2014

Pancreatic cancer has the highest mortality rate of all major cancers and the survival rate has remained low for over 30 years. This is the case because the most common type of pancreatic cancer—known as Pancreatic Ductal Adenocarcinoma (PDAC)—is often diagnosed at later stages in the disease, after it has spread to other parts of the body.

For a number of conditions, measuring levels of proteins in the blood—known as serum biomarkers—can enable physicians to confidently determine whether symptoms are the result of disease. For PDAC, the CA19.9 protein is the only approved biomarker; unfortunately, CA19.9 lacks the sensitivity and specificity required to identify patients with earlier stages of the disease.

A recent study, led by PM and TGRI Clinical Researcher Dr. Ivan Blasutig, addresses this issue by testing a diverse group of new and existing biomarkers for their ability to identify pancreatic cancer.

Full Story

The ORT Times November Issue Now Available
Nov 19, 2014

The UHN Office of Research Trainees (ORT) is proud to announce the November 2014 issue of The ORT Times! The ORT Times is a monthly e-newsletter focused on UHN trainees featuring news and editorials about trainee life, articles to help developing researchers get the most out of their training experience at UHN, tips on career development and research training opportunities within and outside of UHN.

Full Story

Paul Santerre Wins Manning Award
Nov 17, 2014

Dr. Paul Santerre, Techna’s Director, Research Faculty (Physical Sciences), has won the prestigious 2014 Manning Principal Award for his work on surface-modifying macromolecules. Commercialized through Interface Biologics Inc., his invention helps prevent blood clots from forming on plastic devices inserted into the body, such as catheters.

While manufacturers could previously prevent clots by coating devices with anti-coagulant drugs, those coatings would dissolve away over time and enter the body or undergo fouling. To address this issue, Dr. Santerre developed surface modifying macromolecules that can be permanently embedded into the medical device during manufacturing and that have been shown to dramatically reduce clotting. The patented additive, known as EndexoTM, has been incorporated into catheters that are now in use across Canada and the United States. Read more about Dr. Santerre’s achievement in Maclean’s and UofT News.

Full Story


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